Scanner Microarray InnoScan 910 High Density

Ideal tool for reading high-density mircroarrays

With its new detection system, the InnoScan 910 has the highest resolution and reading speed on the market. This user-friendly, two-color scanner is the ideal tool for reading current and future high-density microarrays.

Main Features

Characterized by its simplicity of use, competitive price and superior image quality, the InnoScan 910 is the ideal tool for scanning most high density microarrays currently available on the market.

• High resolution: InnoScan 910 is a high resolution 2-colour fluorescence scanner. It is capable of reading microarrays at a very high image quality with a resolution of 1µm/pixel.
• Speed: Capable of simultaneously reading 2 detection channels in 3.55 minutes (at 10µm/pixel maximum reading area); InnoScan 910 is the fastest scanner on the market with a sweep speed which adjustable from 10 to 35 lines/second.

• Reliable and traceable results: With a barcode reader, InnoScan 910 provides accurate control of acquired images. InnoScan 910 is supplied with a validation slide and proprietary Mapix software which verifies scanner performance.

Given the size of the images obtained (5.74 GB to read an entire slide at 1 µm resolution), Mapix image analysis software has been specially designed to handle large files.

Applications

InnoScan 910 is ideal for reading high density microarrays currently available on the market:

• High density CGH arrays (6X80K, 4X180K)
• High density protein arrays
• Nimblegen HD2 and HD4 slides

In the following application fields:

• Functional genomics: CNV, genotyping, DNA methylation.
• Transcriptomics: Gene expression, miRNA.
• Proteomics: Protein expression, antibody arrays.

Technology

The InnoScan 910 is a confocal detection scanner equipped with 2 extremely sensitive analog photomultiplier tubes (PMT), linear gain over the range of 0.1 to 100% and is capable of detecting from 0 to 1% of gain with a step of 0.01%. This makes it easy for the user to set PMT gains and adjust the fluorescence signal levels for the 2 colours by managing saturation level and equilibrating the 2 channels.

Like the InnoScan 710, the InnoScan 910 uses a real-time autofocus system that offers the advantage of making it adaptable to substrate distortion, thus making the entire reading area completely uniform. Thanks to XDR mode (Extended Dynamic Range), InnoScan scanners have a dynamic range over 10⁶ and are thus capable of detecting the lowest signals while avoiding saturation.

The InnoScan scanners are well known for their excellent photometric properties, particularly in terms of sensitivity and signal-to-noise ratio.

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